Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic https://datingranking.net/escort-directory/columbia-1/ reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men's body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.
Addition
The brand new prevalence from sterility among partners of reproductive age ranges, according to various present, out of 8% to help you twenty-five% [1–3]. Male sterility is the only reason behind sterility for the 20–30% away from times and a factor leading to sterility inside fifty% of all infertility times . The brand new review away from male fertility constantly includes medical examination and analysis on the reference values of your after the sperm parameters: volume, complete sperm fertility, quantity, motility and you can morphology (Table 1) . Reasonable sperm count and/otherwise high quality is available in the ninety% out of partners having virility troubles . Throughout the testing out-of virility, this new levels of male reproductive hormones are reviewed. Recently, brand new molecular composition regarding spunk cells, analyzed of the researching the amount of DNA fragmentation otherwise oxidative stress has been even more considered. Multiple degree use the DNA fragmentation directory (DFI) as the indicative of pregnancy achievements. Considering Evenson and you can Wixon, DFI range away from 3 to 5% in match boys, when you find yourself an excellent DFI of ? 30% try with the less virility . Already laid out hereditary situations, as well as one another chromosomal aberrations and monogenic change, account fully for only about ten–15% away from cases of men sterility . The main cause to own fertility dilemmas can certainly be ecological items. The goal of the analysis was to analyze the connection anywhere between diet plan, opportunity balance and fertility pricing when you look at the men.
Approach out of books browse
A comprehensive literature search of published studies in various languages, was carried out in electronic databases, including: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Review and Google Scholar. Randomized controlled trials, observational and qualitative studies published between 2008 and 2018 (up to and including March) were included. The following keywords related to male infertility, diet, nutrients and their combinations (made by applying operators AND and OR) were used in the search: ‘male infertility’, ‘sperm quality’, ‘idiopathic oligozoospermia’, ‘astenoazospermia’, ‘oligoastenoteratozoospermia’, ‘sperm DNA damage’, ‘nutritional status’, ‘BMI’, ‘obesity’, ‘diet’, ‘nutrition’, dietary pattern’, ‘food’, ‘nutrient’, ‘fatty acids’, ‘antioxidant’, ‘supplementation’, ‘vitamin C’, ‘vitamin E’,’ vitamin A’, ‘folate’, ‘zinc’, ‘selenium’, ‘L-carnitine’, ‘glutathione’, ‘coenzyme Q10‘, ‘N-acetylcysteine’, ‘lycopene’. Reference lists of studies extracted from the primary electronic search were used to identify additional relevant studies.
Semen factor | Site limit (95% trust intervals) |
---|---|
Sperm frequency | 1.5 ml (1.4–1.7) |
Total sperm fertility | 39 million for each squirt (33–46) |
Spunk quantity | 15 million for each ml (12–16) |
Efforts | 58% alive (55–63) |
Progressive motility | 32% (31–34) |
Overall (progressive + nonprogressive) motility | 40% (38–42) |
Morphologically normal forms | 4.0% (step three.0–cuatro.0) |